Bpsbioscience/A-966492/27601-1/5毫克
商品编号：
27601-1
品牌：
bpsbioscience
市场价：
¥3500.00
美元价：
2100.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
MW:324.4Da
CASRegistry#:934162-61-5
Formula:C18H17FN4O
Target:PARP1,PARP2
Background:
A-966492isoneofthemostpotentPARPinhibitors.A-966492displaysexcellentpotencyagainstthePARP-1enzymewithaKiof1nMandanEC50of1nMinawholecellassay.A-966492significantlyenhancestheefficacyofTMZinadose-dependentmanner.Inaddition,A-966492isorallybioavailableacrossmultiplespecies,crossestheblood?brainbarrier,andappearstodistributeintotumortissue.A-966492representsapromising,structurallydiversebenzimidazoleanalogueandisbeingfurthercharacterizedpreclinically.
Description:
A-966492isanovelandpotentinhibitorofPARP1andPARP2withKiof1nMand1.5nM,respectively.
Synonym(s):
2-[2-fluoro-4-[(2S)-pyrrolidin-2-yl]phenyl]-1H-benzimidazole-4-carboxamide
Purity:
≥98%byHPLC
Solubility:
SolubleinDMSO65mg/ml,Water<1mg/ml,Ethanol<1mg/ml
Storage/StABIlity:
Storeatorbelow–20°C.Solidformisstableatleast12monthsfromdateofreceipt,whenstoredasdirected.Donotstoreaqueoussolutionsformorethanoneday.
Reference(s):
PenningTD,etal.JMedChem.2010Apr22;53(8):3142-53.
ScientificCategory:
PARPInhibitor
ProductType:
Inhibitor
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
