Bpsbioscience/人神经营养素-4/90226-A/2µg
商品编号：
90226-A
品牌：
bpsbioscience
市场价：
¥2600.00
美元价：
1560.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Species:Human
HostSpecies:E.coli
MW:14kDa
Genbank#:P34130
a.a:81–210
Background:
Neurotrophinsarewell-knownretrogradesignalingmoleculesthatregulatedifferentiationandcellsurvivalinmanycentralandperipheralneurons.Neurotrophin-4(NT-4)isthemostrecentlydiscoveredneurotrophicfactorinmammalsand,functionally,theleastwellunderstood.LittleisknownabouttheroleofNT-4insupportingthesurvivalofidentifiedclassesofsensoryneurons.MicelackingNT4(NT4/)exhibitalossof~50%oftheneuronsinthenodose-petrosalandgeniculategangliabutnoapparentlossofneuronsinthedorsalrootganglia.
Description:
RecombinantNT-4isadisulfide-linkedhomodimerproteinconsistingoftwo131aminoacidresidues,andmigratesasanapproximately29kDaproteinundernon-reducingandas14kDaunderreducingconditionsinSDS-PAGE.OptimizedDNAsequenceencodingHumanNeurotrophin-4maturechainwasexpressedinE.coli.
UniProt
P34130
Synonym(s):
NT4,Neurotrophin4,Neurotrophin5,NT-4,NTF5,NTF-5,NTF4,NTF-4,NT5
Purity:
≥97%bySDS-PAGEandHPLC
EndotoxinLevel:
<0.1ng/µg(1EU/µg),usingtheLALgelclotmethod.
BIOLOGicalActivity:
TheED50wasdeterminedbythedose-dependentinductionofcholineacetyltransferaseactivityinratbasalforebrainprimaryseptalcellcultures,andwasfoundtobeinarangeof10-50ng/ml.
Formulation:
Lyophilizedfroma0.2µmfilteredPBSsolution,pH7.5.
Format:
lyophilizedprotein
Reconstitution:
Reconstituteat0.1-1.0mg/mlindistilledwater.Thissolutioncanthenbedilutedintootherbuffers.Tomaximizeproductcollectionfromvialsurface,vortexbrieflyandthenspindowntorecollecttheliquid.
Storage/StABIlity:
Thelyophilizedproteinisstableforatleast2yearsfromdateofreceiptwhenstoredat-20°C.Uponreconstitution,storeinworkingaliquotsat+4°Cforuptoonemonth,orat-20°Cforuptosixmonths,inthepresenceofacarrierprotein.Avoidrepeatedfreeze/thawcycles.
Reference(s):
1.J.Biol.Chem.,Feb2008,283:3385-3391.
2.J.Pharmacol.Exp.Ther.,Nov2005,315:796-804.
2.J.Pharmacol.Exp.Ther.,Nov2005,315:796-804.
Warning(s):
Avoidfreeze/thawcycles
AminoAcidSequence:
GVSETAPASRRGELAVCDAVSGWVTDRRTAVDLRGREVEVLGEVPAAGGSPLRQYFFETRCKADNAEEGGPGAGGGGCRGVDRRHWVSECKAKQSYVRALTADAQGRVGWRWIRIDTACVCTLLSRTGRA
ScientificCategory:
Cytokine/GrowthFactors
ProductType:
RecombinantProtein
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
