Bpsbioscience/Human Neurotrophin-3/90225-A/2 µg
商品编号：
90225-A
品牌：
bpsbioscience
市场价：
¥2600.00
美元价：
1560.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Species:Human
HostSpecies:E.coli
MW:14kDa
Genbank#:P20783
a.a:139–257
Background:
NT-3isfoundinneuronsofthecentralnervoussystem.NT-3isexpressedalsoinmusclesanditsexpressionisdown-regulatedindenervatedmuscles.ManyhumangliomasexpressandsecreteNT-3intotheconditionedmedium.SomeproteindomainsofNT-3areidenticalwiththoseofNGFandBDNF.NT-3selectivelysupportsthesurvivalofneuronalcellpopulations,andpreventsthedeathofculturedembryonicratspinalmotorneuronsatpicomolarconcentrations.NT-3hasbeenshowntoenhancesproutingofcorticospinaltractduringdevelopmentandafteradultspinalcordlesion.TheactivitiesofNT-3andBDNFareadditiveinsomesystems.TheBIOLOGicalactivitiesofNT-3aremediatedbyareceptorbelongingtothetrkfamilyofreceptorswithintrinsictyrosine-specificproteinkinaseactivity.NT-3onlybindsweaklytothetrkreceptorwhichisahigh-affinityreceptorforNGF.
UniProt
P20783
Synonym(s):
NT3,Neurotrophin3,NT-3,NGF-2,NerveGrowthFactor2,NTF3
Purity:
≥97%bySDS-PAGEandHPLC
EndotoxinLevel:
<0.1ng/µg(1EU/µg),usingtheLALgelclotmethod.
BiologicalActivity:
TheED50wasdeterminedbythedose-dependentinductionofcholineacetyltransferaseactivityinratbasalforebrainprimaryseptalcellcultureswasfoundtobeintherangeof10-50ng/ml.
Formulation:
Lyophilizedfroma0.2µmfilteredPBSsolution,pH7.5.
Format:
lyophilizedprotein
Reconstitution:
Reconstituteat0.1-1.0mg/mlindistilledwater.Thissolutioncanthenbedilutedintootherbuffers.Tomaximizeproductcollectionfromvialsurface,vortexbrieflyandthenspindowntorecollecttheliquid.
Storage/StABIlity:
Thelyophilizedproteinisstableforatleast2yearsfromdateofreceiptwhenstoredat-20°C.Uponreconstitution,storeinworkingaliquotsat+4°Cforuptoonemonth,orat-20°Cforuptosixmonths,inthepresenceofacarrierprotein.Avoidrepeatedfreeze/thawcycles.
Reference(s):
1.J.Immunol.,Apr2009,182:4705-4712.
2.J.Neurosci.,Jan2009,29:575-587.
3.J.CellBiol.,Dec2006,175:1029-1042.
2.J.Neurosci.,Jan2009,29:575-587.
3.J.CellBiol.,Dec2006,175:1029-1042.
Warning(s):
Avoidfreeze/thawcycles
AminoAcidSequence:
YAEHKSHRGEYSVCDSESLWVTDKSSAIDIRGHQVTVLGEIKTGNSPVKQYFYETRCKEARPVKNGCRGIDDKHWNSQCKTSQTYVRALTSENNKLVGWRWIRIDTSCVCALSRKIGRT
ScientificCategory:
Cytokine/GrowthFactors
ProductType:
RecombinantProtein
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
