Bpsbioscience/L3MBTL1，GST标签/55000/100µg
商品编号：
55000
品牌：
bpsbioscience
市场价：
¥8800.00
美元价：
5280.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Species:Human
HostSpecies:E.coli
MW:65.5kDa
Genbank#:NM_015478
Tag(s):N-terminalGST-tag
a.a:191–530
Background:
Polycombgroup(PcG)proteinthatspecificallyrecognizesandbindsmono-anddimethyl-lysineresiduesontargetproteins,thereyactingasareaderofanetworkofpost-translationalmodifications.PcGproteinsmaintainthetranscriptionallyrepressivestateofgenes:actsasachromatincompactionfactorbyrecognizingandbindingmono-anddimethylatedhistoneH1b/HIST1H1EatLys26(H1bK26me1andH1bK26me2)andhistoneH4atLys-20(H4K20me1andH4K20me2),leADIngtocondensechromatinandrepresstranscription.Recognizesandbindsp53/TP53monomethylatedatLys-382,leadingtorepressp53/TP53-targetgenes.AlsorecognizesandbindsRB1/RBmonomethylatedatLys-860.ParticipatesintheETV6-mediatedrepression.Probablyplaysaroleincellproliferation.Overexpressioninducesmultinucleatedcells,suggestingthatitisrequiredtoaccomplishnormalmitosis.
Description:
Humanlethal(3)malignantbraintumor-likeprotein1(L3MBTL1),GenBankAccessionNo.NM_015478,a.a.191-530withN-terminalGST-tag,MW=65.5kDa,expressedinanE.colicellexpressionsystem.
UniProt
Q9Y468
Synonym(s):
lethal(3)malignantbraintumor-likeprotein1,L3MBTL1
Formulation:
40mMTris-HCl,pH8.0,110mMNaCl,2.2mMKCl,1mMDTT,20mMglutathione,and20%glycerol
Format:
Aqueousbuffersolution
Storage/StABIlity:
≥ 6monthsat-80°C
Application(s):
UsefulforthestudyofPolycombgroup(PcG)proteins,proteinbindingassays,screeninginhibitors,andselectivityprofiling.
Reference(s):
1.Koga,H., etal.,Oncogene. 1999Jul 1;18(26):3799-809.
2.Trojer,P., etal.,Cell. 2007Jun 1;129(5):915-28.
3.Min,J., etal.Nat.Structl.&Mol. Biol. 2007;14:1229–1230.
Warning(s):
Avoidfreeze/thawcycles
ScientificCategory:
Methyl-lysineReader
ProductType:
RecombinantProtein
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
