Bpsbioscience/ABL2, His-tag/40417/10 µg
商品编号：
40417
品牌：
bpsbioscience
市场价：
¥7800.00
美元价：
4680.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Species:Human
HostSpecies:Sf9insectcells
MW:132kDa
Genbank#:NM_005158
Tag(s):N-terminalHis-tag
a.a:38–end
Background:
ABL2(orARG)isanonreceptorcytoplasmictyrosinekinasewhichiscloselyrelatedtobutdistinctfromABL1.ThesimilarityofABL1andABL2includesthetyrosinekinasedomainsandextendsamino-terminaltoincludetheSH2andSH3domains.ABL2isinvolvedintranslocationwiththeETV6geneinhumanleukemiaandhasanalteredexpressioninseveralhumancarcinomas(1).TwoisoformsofABL2withdifferentN-termini(1Aand1B)havebeenidentified.TheC-terminaldomainofABL2containstwoF-actin-bindingsequencesthatperformanumberofactionsrelatedtocellmorphologyandmotilitybyinteractingwithactinfilaments(2).
Description:
RecombinanthumanABL2(a.a.38-end),withN-terminalHis-tag,expressedinSf9insectcellsviaabaculovirusexpressionsystem.
Synonym(s):
ARG;ABLL
Purity:
≥75%
Formulation:
50mMsodiumphosphatepH7.0,300mMNaCl,150mMimidazole,0.1mMPMSF,0.2mMDTT,25%glycerol
Format:
Aqueousbuffersolution
Storage/StABIlity:
>6monthsat-80°C.
Application(s):
Usefulforthestudyofenzymekinetics,screeninginhibitors,andselectivityprofiling.
Reference(s):
1.Barila,D.etal:AnintramolecularSH3-domaininteractionregulatesc-Ablactivity.NatureGenet.18:280-282,1998.
2.Griesinger,F.etal:IdentificationofanETV6-ABL2fusiontranscriptincombinationwithanETV6pointmutationinaT-cellacutelymphoblasticleukaemiacellline.BrJHaematol.2002Nov;119(2):454-8.
2.Griesinger,F.etal:IdentificationofanETV6-ABL2fusiontranscriptincombinationwithanETV6pointmutationinaT-cellacutelymphoblasticleukaemiacellline.BrJHaematol.2002Nov;119(2):454-8.
Warning(s):
Avoidfreeze/thawcycles
ScientificCategory:
Kinase/Serine-Threonine
ProductType:
RecombinantProtein
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
