Bpsbioscience/ABT-888 (Veliparib)/27101/10 mg
商品编号：
27101
品牌：
bpsbioscience
市场价：
¥5600.00
美元价：
3360.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
MW:244.3Da
CASRegistry#:912444-00-9
Formula:C13H16N4O
Description:
ABT-888(Veliparib)isapotentinhibitorofbothPARP-1andPARP-2.IntheMX-1breastxenograftmodel(BRCA1deletionandBRCA2mutation),ABT-888potentiatedcisplatin,carboplatin,andcyclophosphamide,causingregressionofestablishedtumors,whereaswithcomparabledosesofcytotoxicagentsalone,onlymodesttumorinhibitionwasexhibited.
Synonym(s):
Veliparib
Purity:
≥99%byHPLC
BIOLOGicalActivity:
ABT-888(Veliparib)isapotentinhibitorofbothPARP-1andPARP-2by[3H]NAD+withKiof5.2nmol/Land2.9nmol/L,respectively.ABT-888inhibitedPARP-1withIC50of4.4nMusingBPSBiosciencePARP1ChemiluminescentAssayKit(Cat.#80551).
Solubility:
SolubleinDMSO.
Format:
Whitetobeigepowder.
Storage/StABIlity:
Storeatorbelow–20°C.Solidformisstableatleast12monthsfromdateofreceipt,whenstoredasdirected.Donotstoreaqueoussolutionsformorethanoneday.
Reference(s):
1.Donawho,C.K.,etal.,ClinicalCancerResearchMay200713;2728.
2.Sanchez,E.V.,etal.,Meeting:2009ASCOAnnualMeeting.Citation:JClincalOncol.27:15s,2009(suppl;abstr11028).
3.Liu,SK.,etal.,RADIotherOncol.2008Aug;88(2):258-68.
2.Sanchez,E.V.,etal.,Meeting:2009ASCOAnnualMeeting.Citation:JClincalOncol.27:15s,2009(suppl;abstr11028).
3.Liu,SK.,etal.,RADIotherOncol.2008Aug;88(2):258-68.
ScientificCategory:
PARP
ProductType:
Inhibitor
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
