Bpsbioscience/Anti-CD47 Antagonist Antibody/79065-1/50 µg
商品编号:
79065-1
品牌:
bpsbioscience
市场价:
¥6900.00
美元价:
4140.00
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Species:Human
HostSpecies:HEK293
MW:HeavyChain:51kDa,LightChain:27kDa
Clonality:Monoclonal
Isotype:IgG1
Background:
ClusterofDifferentiation47,orCD47,playsanessentialroleincellgrowth,death,migration,andadhesion.CD47bindingtoSIRP-αmediatesphagocytosisbysendinga“donoteatme”signaltophagocytes.CD47proteinsareoftenoverexpressedbytumorcellsasameansforthemtoescapephagocytosis.Asaresult,canceroustumorcellshavetheABIlitytoproliferateandevadetheimmunesystem.
Description:
Anti-CD47recombinanthumanantagoNISTantibodyrecognizingtheSIRP-αorSIRP-үbindingregionofhumanCD47.Thisantibodyhasnotbeentestedforcross-reactivitywithanyotherspecies.
Formulation:
8mMPhosphate,pH7.4,110mMNaCl,2.2mMKCl,and20%glycerol
Purification:
ProteinAaffinitychromato-graphyfromHEK293supernatants.
Storage/Stability:
Stableforatleast12monthsat-80°C.Protectfromlight.Avoidfreeze/thawcycles.Storedilutedantibodywithcarrierprotein(BSA0.1–0.5%)at4°C,stablefor2weeks.
Application(s):
UsefulasanantagonisttoblockCD47signalingandbindingtoSIRP-αorSIRP-үinbiochemicalassays.
Reference(s):
1.Vernon-Wilson,E.F.etal.,Eur.J.Immunol.2000;30(8):2130-2137.
2.Majeti,R.etal.,Cell.2009;138(2):286-299.
ScientificCategory:
Immunotherapy
ProductType:
Antibody
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品牌介绍
bpsbioscience简介:为生命科学研究提供ELISA试剂盒(仅供科研)、抗体和抗原(仅供科研)、流式抗体,使您的检测结果更稳定可靠,用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀,吸附性好,空白值低,孔底透明度高,代做ELISA实验等。