Bpsbioscience/HSP90αN端结构域分析试剂盒/50293/96反应-免疫在线蚂蚁淘旗下平台

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Bpsbioscience/HSP90αN端结构域分析试剂盒/50293/96反应

商品编号： 50293

品牌： bpsbioscience

市场价： ¥9000.00

美元价： 5400.00

产地：美国(厂家直采)

公司：

产品分类：其它检测试剂盒

公司分类： Other_kits

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商品介绍

Background:

Hsp90αisamolecularchaperonewithessentialfunctionsinmaintainingtransformation.InhibitionofHsp90αfunctionhasbeenshowntoplayaroleintumOrigenesisanddiseaseprogression.

Description:

TheHSP90αAssayKitisdesignedforidentificationofHSP90αinhibitorsusingfluorescencepolarization.TheassayisbasedonthecompetitionoffluorescentlylabeledgeldanamycinforbindingtopurifiedrecombinantHSP90α.ThekeytotheHSP90αAssayKitisthefluorescentlylabeledgeldanamycin.Usingthiskit,onlyonesimplesteponamicrotiterplateisrequiredforHSP90αreactions.ThefluorescentlylabeledgeldanamycinisincubatedwithasamplecontainingHSP90αenzymetoproduceachangeinfluorescentpolarizationthatcanthenbemeasuredusingafluorescencereader.

UniProt

P07900

Synonym(s):

HSP90a,HeatShockProtein90a,HSP90alpha,HSP90α

SuppliedAs:

TheHSP90αinhibitorscreeningassaykitcomesinaconvenient96-wellformat,withpurifiedHSP90αenzyme,fluorescentlylabeledgeldanamycinandHSP90αassaybufferfor96enzymereactions.

Contraindications:

DMSO>1%,strongacidsorbases,ionicdetergents,highsalt

Format:

COMPONENTS:

Instructionsforuse:

Seedatasheetfordetailedprotocol.

Storage/StABIlity:

Stableforatleast12monthsfromdateofreceipt,whenstoredasdirected.Kitcomponentsrequiredifferentstorageconditions.Besuretostoreeachcomponentatthepropertemperatureuponarrival.

Application(s):

GreatforstudyingenzymekineticsandscreeningsmallmolecularinhibitorsfordrugdiscoveryandHTSapplications.

Reference(s):

1.Kim,J.,etal.JBiomolScreening2004,9(5):375-381.
2.Howes,R.,etal.AnalBiochem2006,350:202-213.

ApplicationReference(s):
1. RationalDesignofSelectiveAdenine-BasedScaffoldsforInactivationofBacterialHistidineKinases(2017)
2. ThequinonemethideaurinisaheatshockresponseinducerthatcausesproteotoxicstressandNoxa-dependentapoptosisinmalignantmelanomacells(2015)
3.HerbimycinsD-F,ansamycinanaloguesfromStreptomycessp.RM-7-15(2013)

Warning(s):

Avoidfreeze/thawcycles

ScientificCategory:

HeatShockProteins

ProductType:

AssayKit

Datashownislot-specific.Contactusforspecificinformationonotherlots.

品牌介绍

bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。

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