Bpsbioscience/4-iodo-SAHA/27205/50 mg
商品编号：
27205
品牌：
bpsbioscience
市场价：
¥3100.00
美元价：
1860.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
MW:390.2Da
CASRegistry#:1219807-87-0
Formula:C14H19IN2O3
Description:
4-iodo-SAHAisahydrophobicderivativeofSAHA,aclassIandclassIIhistonedeacetylase(HDAC)inhibitor.SimilartoSAHA,itdemonstrates>60%inhibitionofHDAC1andHDAC6activityinadeacetylaseactivityassayat1µM.
Purity:
≥98%byHPLC
BIOLOGicalActivity:
4-iodo-SAHAinhibitsSKBR3breast-derivedandHT29colon-derivedcelllineproliferationwithEC50valuescomparabletothatofSAHA(1.1µMand0.95µMversus2.1µMand2µM,respectively).Ithas10timestheinhibitionstrengthofU937leukemiacellproliferationincomparisontoSAHA(0.12µMversus1.2µM,respectively).
Solubility:
Solubilityinethanolis0.2mg/mland30mg/mlinDMSOandDMF.First,dissolveinDMSOthendilutewiththeaqueousbufferofchoice.
Format:
Acrystallinesolid
Storage/StABIlity:
Storeatorbelow–20°C.Solidformisstableatleast12monthsfromdateofreceipt,whenstoredasdirected.Donotstoreaqueoussolutionsformorethanoneday.
Reference(s):
Salmi-Smail,C.,etal.,J.Med.Chem.2010;53:3038–3047.
ScientificCategory:
HDAC
ProductType:
Inhibitor
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
