Bpsbioscience/（S）-HDAC-42/27208/1 mg
商品编号：
27208
品牌：
bpsbioscience
市场价：
¥2000.00
美元价：
1200.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
MW:312.4Da
CASRegistry#:935881-37-1
Formula:C8H20N2O3
Description:
(S)-HDAC-42isastronginhibitorofHDACs.ItdecreasestheviABIlityofprostatecancercelllinesbyincreasingtheexpressionofp21andtheacetylationofhistoneH3whiledecreasingAktphosphorylationandBcl-XLexpression.TheinhibitorsuppressesthegrowthofPC-3tumorxenografts,reducinglevelsofphospho-AktandBcl-XLproteinintumors.
Purity:
≥95%byHPLC
BIOLOGicalActivity:
(S)-HDAC-42inhibitsHDACswithIC50=16nMinvitro.
Solubility:
Solubleinethanol,DMSOandDMF,whichshouldbepurgedwithaninertgas.Solubilityinthesesolventsis~20mg/ml.Fororganicsolvent-freeaqueoussolutions,preparebydirectlydissolvingthecrystallinecompoundinaqueousbuffers.
Format:
Acrystallinesolid
Storage/Stability:
Storeatorbelow–20°C.Solidformisstableatleast12monthsfromdateofreceipt,whenstoredasdirected.Donotstoreaqueoussolutionsformorethanoneday.
Reference(s):
1.Lu,Q.,etal.,J.Med.Chem.2005;48:5530-5535
2.Kulp,S.K.,etal.,Clin.CancerRes.2006;12(17):5119-5206.
2.Kulp,S.K.,etal.,Clin.CancerRes.2006;12(17):5119-5206.
ScientificCategory:
HDAC
ProductType:
Inhibitor
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
