Bpsbioscience/人BAFF-R（CD268）/90103-B/50µg
商品编号：
90103-B
品牌：
bpsbioscience
市场价：
¥4100.00
美元价：
2460.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Species:Human
HostSpecies:E.coli
MW:9kDa
Genbank#:Q96RJ3
a.a:1–78
Background:
TheBcell-activatingfactorfromtheTNFfamily(BAFF),isemergingasanimportantregulatorofBcellandTcellresponses.BAFFwasoriginallyidentifiedasafactorresponsIBLeforBcellsurvivalandmaturation.BAFFbindstoseveralreceptors.Theseincludetransmembraneactivatorandcalciummodulatorandcyclophilinligandinteractor(TACI),BAFF-R(BR3),andBcellmaturationAg(BCMA).BAFF-RappearstobeparticularlyimportantfortheregulationofBcellsurvivalandmaturationinthespleen,becauseA/WySnJmiceexpressingadefectiveBAFF-RhavedisruptedBcellmaturation,similartothatseeninBAFF-deficientmice.
Description:
RecombinanthumanBAFF-R(Bcell-activatingfactorfromtheTNFfamily),alsoknownasCD268,isadisulfide-linkedmonomericproteinconsistingof76a.a.andmigratesasanapproximately9kDaproteinunderreducingandnon-reducingconditions.OptimizedDNAsequenceencodinghumanBAFF-RextracellulardomainwasexpressedinE.coli.
UniProt
Q96RJ3
Synonym(s):
BAFF-R,Bcell-activatingfactorfromtheTNFfamily,CD268
Purity:
≥95%bySDS-PAGEandHPLC
EndotoxinLevel:
<0.1ng/µg(1EU/µg),usingtheLALgelclotmethod.
Formulation:
Lyophilizedfroma0.2µmfilteredsolutioncontaining2.5%glycine,0.5%sucrose,0.01%Tween-80,5mMglutamicacid,pH4.5.
Format:
lyophilizedprotein
Reconstitution:
Reconstituteat0.1-1.0mg/mlindistilledwater.Thissolutioncanthenbedilutedintootherbuffers.Tomaximizeproductcollectionfromvialsurface,vortexbrieflyandthenspindowntorecollecttheliquid.
Storage/Stability:
Thelyophilizedproteinisstableforatleast2yearsfromdateofreceiptwhenstoredat-20°C.Uponreconstitution,storeinworkingaliquotsat+4°Cforuptoonemonth,orat-20°Cforuptosixmonths,inthepresenceofacarrierprotein.Avoidrepeatedfreeze/thawcycles.
Reference(s):
1.TheeffectsofBAFFandBAFF-R-fcfusionproteininimmunethrombocytopenia.Blood,Dec2009,114:5362-5367.
2.c-relintheregulationofBAFF-RexpressioninmalignanthumanBcells.Blood(ASHAnnualMeetingAbstracts),Nov2009,114:2400.
2.c-relintheregulationofBAFF-RexpressioninmalignanthumanBcells.Blood(ASHAnnualMeetingAbstracts),Nov2009,114:2400.
Warning(s):
Avoidfreeze/thawcycles
AminoAcidSequence:
MRRGPRSLRGRDAPAPTPCVPAECFDLLVRHCVACGLLRTPRPKPAGASSPAPRTALQPQESVGAGAGEAALPLPGLL
ScientificCategory:
Cytokine/GrowthFactors
ProductType:
RecombinantProtein
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
