Bpsbioscience/Anti&ndash；CIITA多克隆抗体/25214/50µg
商品编号：
25214
品牌：
bpsbioscience
市场价：
¥7100.00
美元价：
4260.00
产品分类：
多克隆抗体
公司分类：
Polyclonal_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
HostSpecies:Rabbit
Clonality:polyclonal
Background:
CIITA(UniProtKB/Swiss–ProtentryP33076)isessentialfortranscriptionalactivityoftheHLAclassIIpromoter.Itmayactinacoactivator–likefashionthroughprotein–proteininteractionsbycontactingfactorsbindingtotheproximalMHCclassIIpromoter,ortoelementsofthetranscriptionmachinery.AlternativelyCIITAmayactivateHLAclassIItranscriptionbymodifyingproteinsthatbindtotheMHCclassIIpromoter.DefectsinCIITAcausebarelymphocytesyndrometypeII(BLSII);alsoknownashereditaryMHCclassIIdeficiencyorHLAclassII–deficientcombinedimmunodeficiency.
Description:
PolyclonalantibodyraisedinrabbitagainsthumanCIITAprotein(MHCclassIItransactivator),usingarecombinantprotein.
Synonym(s):
C2TA,MHC2TA
AssayConditions:
ChIPresultsobtainedwiththeantibodydirectedagainstCIITA
ChIPassayswereperformedusingNALMcells(acelllinederivedfromhumanpre-Bleukemia),theantibodyagainstCIITA(Cat.#25214)andoptimizedprimersetsforPCR.Shearedchromatinfrom2millioncellsandrespectively5and7µgofantibodywereusedperChIPexperiment.Ananti-FLAGantibody(lane2)wasusedasnegativeIPcontrol.Figure1showstheresultoftheend-pointPCRwithprimersforHLA_DRA,usedaspositivecontrol(lowerpanel)andforHLA_DOB,usedanegativePCRcontrol(upperpanel).
Concentration:
50µg/50µl
Formulation:
PBScontaining0.05%azideand0.05%ProClin300.
SpeciesReactivity:
Human
Purification:
Affinitypurified
Immunogen:
recombinantprotein
Format:
Aqueousbuffersolution
Storage/StABIlity:
Storeat–80°Cforupto2years.Centrifugeafterfirstthawtomaximizeproductrecovery.Aliquottoavoidrepeatedfreeze/thawcycles.Aliquotsmaybestoredat–20°Cforatleastonemonth.
Application(s):
ChIP(5–7µg/IP)
Notes:
TheoptimalantibodyamountperIPshouldbedeterminedbytheend–user.Werecommendtesting1–10µgperIP
Warning(s):
Avoidfreeze/thawcycles
ScientificCategory:
Antibodies
ProductType:
Antibody
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
