Bpsbioscience/BCL-2, His-tag/50272/100 µg
商品编号：
50272
品牌：
bpsbioscience
市场价：
¥8300.00
美元价：
4980.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Species:Human
HostSpecies:E.coli
MW:27kDa
Genbank#:P10415
Tag(s):C-terminalHis-tag
a.a:1–211
Background:
Suppressesapoptosisinavarietyofcellsystemsincludingfactor-dependentlymphohematopoieticandneuralcells.RegulatescelldeathbycontrollingthemitochondrialmembranepermeABIlity.Appearstofunctioninafeedbackloopsystemwithcaspases.Inhibitscaspaseactivityeitherbypreventingthereleaseofcytochromecfromthemitochondriaand/orbybindingtotheapoptosis-activatingfactor(APAF-1).
Description:
HumanBcl-2(GenBankAccessionNo.P10415),a.a.1-211withC-terminalHis-tag,MW=27kDa,expressedinanE.coliexpressionsystem.
UniProt
P10415
Synonym(s):
Bcl,Bcl2,Bcelllymphoma2
AssayConditions:
FollowingtheprotocolforBPSCat.#50222.Briefly,BCL-2wascombinedwithBCL-2peptideligandinTR-FRETassaybufferalongwithanti-HisTbdonoranddyelabeledacceptor.VaryingconcentrationsofABT199wereaddedandthereactionwasincubatedatroomtemperaturefor2hoursfollowedbyfluorescentintensitymeasurements.
Formulation:
40mMTris-HCl,pH8.0,110mMNaCl,2.2mMKCl,3mMDTT,20%glycerol,and200mMimidazole
Format:
Aqueousbuffersolution
Application(s):
Usefulforthestudyofapoptosis,screeninginhibitors,andselectivityprofiling.
Reference(s):
1.LabiV.etal.,CellDeathDiffer.2008Jun;15(6):977-87.
2.RongY.P.etal.,MolCell.2008Jul25;31(2):255-65.
2.RongY.P.etal.,MolCell.2008Jul25;31(2):255-65.
Warning(s):
Avoidfreeze/thawcycles
ScientificCategory:
Apoptosis
ProductType:
RecombinantProtein
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
